The exploitation of low-to-moderate geothermal aquifers is similar to development of non-thermal aquifers in some respects. However, there are some problems which are peculiar to these resources. Although the hydrostratigraphic unit may be areally extensive, the thermal reservoir itself is typically of limited areal extent. So, in addition to being constrained by the physical attributes of the system, resource development can be inhibited by regulations which have their origins removed from these types of systems. Examples of how the regulations for disposal of heat-spent thermal effluent via Class V injection wells influenced development of four low-to-moderate temperature geothermal reservoirs are discussed